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APVMA Has Approved the Registration of New active Constituent - Glufosinate-P-ammonium
2024/6/28 14:18:10

APVMA Has Approved the Registration of New active Constituent - Glufosinate-P-ammonium

On March 6, 2024, the Australian Pesticides and Veterinary Medicines Authority (APVMA) has approved the registration of new active constituent - Glufosinate-P-ammonium. 


Summary of the APVMA’s evaluation of Glufosinate-P-ammonium active constituent

The APVMA has evaluated the chemistry aspects of Glufosinate-P-ammonium active constituent (physico-chemical properties, stability, identification, manufacturing process, quality control procedures, batch analysis results and analytical methods) and found them to be acceptable.

The APVMA has completed a toxicological evaluation of Glufosinate-P-ammonium. An acceptable daily intake (ADI) for Glufosinate-ammonium as the racemate or S-enantiomer (i.e., Glufosinate-P-ammonium) of 0.01 mg/kg bw/d has been set. This is based on a No-Observed Effect Level (NOAEL) of 1 mg/kg bw/d in a capsule study in dogs, after applying a safety factor of 100. An Acute Reference Dose (ARfD) for Glufosinate-ammonium as the racemate or S-enantiomer (i.e., Glufosinate-P-ammonium) of 0.01 mg/kg bw has been set based on a NOAEL of 1 mg/kg bw/d in a capsule study in dogs.

Based on the information available, there is potential for trace quantities of cyanide to be present in technical Glufosinate-P-ammonium. It is proposed therefore to include a maximum limit of 10 mg/kg for cyanide in the standard for Glufosinate-P-ammonium.

Glufosinate-P-ammonium is the L isomer of Glufosinate-ammonium which is included in Schedule 5 of the Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP). No amendments are required for the SUSMP.

On the basis of the data provided, and the toxicological assessment, it is proposed that the following APVMA Active Constituent Standard be established for Glufosinate-P-ammonium:

Table 1: Proposed APVMA Active Constituent Standard for Glufosinate-P-ammonium



And now, King Quenson provides farmers an formulation of Glufosinate-P-ammonium, King's Proud.

Feature and benefits of King's Proud:

Multiplied Activity

Broad-Spectrum Weeds Control

Fast-Acting and Long-Lasting Protection

Safer for Crops and Environmental Friendly

Multiplied Activity

The herbicidal activity of King's Proud is 1.5 to 2 times that of the conventional Glufosinate-ammonium. Therefore the dosage of King's Proud can be reduced 50% (e.g. 20% SL, 1.5-2.25 L/ha), which can significantly reduce the cost of technical materials, adjuvants, packaging and transportation. The direct benefit to farmers is that the actual cost of using King's Proud is not only much lower than conventional Glufosinate-ammonium, it is even at the same cost level as Glyphosate.


Broad-Spectrum Weeds Control

King's Proud can effectively control most of annual and perennial broad-leaved weeds and grasses, especially to Glyphosate-resistant weeds such as Goosegrass (Eleusine indica), Horseweed (Erigeron canadensis) and etc.

In addition, there have been no reports of weed resistance developed to King's Proud.

Fast-Acting and Long-Lasting Protection

After using King's Proud, the treated weeds stop growing within the first day of application. The visual symptoms appear in 2 to 3 days, include yellowing, chlorosis, wilting, scorching, necrosis and etc. And the complete death of the weeds usually occurs in 7 to 10 days. If the temperature is lower to 15-20°C the complete death will occur in 15 to 20 days.

Meanwhile, King's Proud provides long-lasting protection for 25 to 30 days for sensitive weeds and 10 to 20 days for moderate sensitive weeds.


Safer for Crops and Environmental Friendly

King's Proud degrades rapidly in the soil, so it does not harm the roots or the soil. As King's Proud only affects the parts of the plant where it is applied, farmers can rely on it to guarantee a high level of crop safety.

Meanwhile, King's Proud is more environmental friendly as it only contains the active L-glufosinate, resulting in a 50% reduction in the release of inactive isomer into the soil.


If you have a need, you can contact us at any time:


Tel: 86-755-86612760, 86-755-86612793


Source: APVMA

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